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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

Rel Products, Inc. ATD-424 24 Adjustable Wrench With 2-1 2 Opening

By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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Remotec ZDS-110NA - Z-Wave Plug-in Dimmer

By Connor Emdin
September 26, 2018

Rs pro ESD 120 mm Stahl FlachzangeRs Pro Set Tournevis, 6 Pièces - Ingénieurs Troué ; Évasé ; PozidrivRTI XP-3 Advanced Control ProcessorRubi Wheel for Manual Tile Cutter 18mm Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Résistant à L'Eau Housse Predection Moto Medium Pièce Numéro 5105 par Laser - Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

RHT-1412 Molex Crimp Tool Crimper Warranty 30 days

By Martina McGrath, MD
July 18, 2018

S&G TOOL AID 88175 Dolly SpoonS-37 S37 FCI Burndy Crimp Die Crimper Warranty 30 daysSAE Metric Combo Wrench Set (19 Pieces)Saldatore, basso voltaggio, MT-100, Intelliheat, 230 V RICHMONT, TORQUE WRENCH, LTC 2, 150 - 750 INCH LBS

QLT by Marshalltown RL801 Roll Lifter Drywall npvmrv3665-Other Hand Tools

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New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is ... Read moreabout the condition


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Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

RIDGID 12698 18 RapidGrip Aluminium Pipe Wrench, 18-inch

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

RIDGID 31025 Model 18 Heavy-Duty Straight Pipe Wrench, 18-inch Plumbing Wrench

By Martina McGrath, MD
June 5, 2018


RIDGID 31100 Model 818 Aluminum Straight Pipe Wrench, 18-inch Plumbing Wrench

Samsung Soundbar Home Audio HW-HM45 Sound System Soundbar 3870K

By Lea Borgi, MD
May 16, 2018

Samurai Kishi Folding Curved Saw Large Teeth 180 mm FC-180-LH Hand Kanzawa JapanSash Cramp 1050mm Capacity - Draper Expert 10960Savant Smart Control 7 SSC-0007-00 SmartControl REV 20 Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”